Construire son avenir
Faculté de Médecine Henri Warembourg

Fibrosis in immune-mediated inflammatory diseases: from pathophysiology to innovative treatment

Event Date : 29/06/2021

The Institut for Translational Research in Inflammation (INFINITE U1286 ULille | Inserm | CHU Lille), in collaboration with the translational gastroenterology laboratory of the Interdisciplinary Center for Biomedical Research (GIGA) from the University of Liège | CHU Liège directed by Prof. Edouard LOUIS, organizes an International Symposium

The scientific event will bring together national and international experts on fibrosis complicating chronic inflammatory diseases (MIC) over one day. Fibrosis is a major health problem in modern societies. It is a complication of a broad spectrum of chronic diseases including IBD and it has a significant impact on morbidity and mortality, mainly due to organ dysfunction. Almost 45% of deaths in the developed world are attributable to fibrosis. However, the cellular and molecular mechanisms leading to fibrosis in MICs are far from fully understood. The consequence is the virtual absence of approved treatment, contrasting with the major impact of this complication

INFINITE has among its research themes the understanding of the mechanisms of fibrosis complicating chronic inflammatory diseases in order to lead to innovative treatments

The translational gastroenterology laboratory of the GIGA research center (ULiège) focuses on understanding the pathophysiological aspects of inflammatory bowel diseases and their consequences, such as intestinal fibrosis.

Provisional program

Clinical Session

Speakers

Topics

Moderators: Pr David Launay et Pr Renaud Louis 

9h15

INTRODUCTION

 

 

 

9h30-9h45

Oral clinical communication 1

Liège

Julien GUIOT

Fibrosing lung diseases

9h45-10h00

Oral clinical communication 2

Liège

Julien GUIOT

Lung fibrosis in rheumatic diseases 

10h00-10h15

Oral clinical communication 3

Lille

Vincent SOBANSKI

Endotypes in systemic fibrosing diseases

10h15-10h30

Oral clinical communication 4

Lille

Guillaume Lassailly

 

10h30-10h45

Break

 

 

 

10h45-11h15

Plenary Local speaker

Liège

Edouard LOUIS

Management of stenonis in Crohn Disease

11h15-11h45

Plenary International speaker

Zurich

Oliver DISTLER

Innovative treatment in fibrosis: application in inflammatory disease stages

11h45-13h15

Break

 

 

 

Fundamental Session

Speakers

Topics

Moderators: Laurent Dubuquoy et Marie-Alice Newis

13h15-14h15

Plenary International speaker

 

Florian RIEDER

Mechanisms of intestinal fibrosis in IBD

14h15-14h45

Plenary Local speaker

Lille

Silvia SPECA

The life cycle and heterogeneity of fibroblasts: an overview of their role in IMIDs-associated fibrotic diseases outcome

14h45-15h00

Break

 

 

 

15h00-15h15

Fundamental Oral Communication 1

Lille

Aurélien CHEPY

Profibrotic role of autoantibodies: systemic sclerosis paradigm

15h15-15h30

Fundamental Oral Communication 2

Lille

Line Ntandja Wandji

 

15h30-15h45

Fundamental Oral Communication 3

Liège

Sophie VIEUJEAN

AG2R role inintestinal fibrosis in Crohn disease

15h45-16h00

Fundamental Oral Communication 4

Liège

Celine DEROYER

Fibrosis in arthrosis: role of Cemip

16h

Conclusion